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Research Article

Direct Quantification of Cell-Free, Circulating DNA from Unpurified Plasma

  • Sarah Breitbach,

    Affiliation: Department of Sports Medicine, Rehabilitation and Prevention, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Suzan Tug,

    Affiliation: Department of Sports Medicine, Rehabilitation and Prevention, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Susanne Helmig,

    Affiliation: Department of Sports Medicine, Rehabilitation and Prevention, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Daniela Zahn,

    Affiliation: Department of Health Psychology, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Thomas Kubiak,

    Affiliation: Department of Health Psychology, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Matthias Michal,

    Affiliation: Department of Psychosomatic Medicine and Psychotherapy, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Tommaso Gori,

    Affiliation: Department of Cardiology, Angiology and Internal Medicine, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Tobias Ehlert,

    Affiliation: Department of Sports Medicine, Rehabilitation and Prevention, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Thomas Beiter,

    Affiliation: Department of Sports Medicine, Medical Clinic, Eberhard-Karls-University of Tuebingen, Tuebingen, Germany

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  • Perikles Simon mail

    simonpe@uni-mainz.de

    Affiliation: Department of Sports Medicine, Rehabilitation and Prevention, Johannes Gutenberg-University of Mainz, Mainz, Germany

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  • Published: March 03, 2014
  • DOI: 10.1371/journal.pone.0087838

About the Authors

Sarah Breitbach, Suzan Tug, Susanne Helmig, Tobias Ehlert, Perikles Simon
Department of Sports Medicine, Rehabilitation and Prevention, Johannes Gutenberg-University of Mainz, Mainz, Germany
Daniela Zahn, Thomas Kubiak
Department of Health Psychology, Johannes Gutenberg-University of Mainz, Mainz, Germany
Matthias Michal
Department of Psychosomatic Medicine and Psychotherapy, Johannes Gutenberg-University of Mainz, Mainz, Germany
Tommaso Gori
Department of Cardiology, Angiology and Internal Medicine, Johannes Gutenberg-University of Mainz, Mainz, Germany
Thomas Beiter
Department of Sports Medicine, Medical Clinic, Eberhard-Karls-University of Tuebingen, Tuebingen, Germany

Corresponding Author

Email: simonpe@uni-mainz.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SB PS ST DZ TK MM TG SH TE. Performed the experiments: SB SH TE TB. Analyzed the data: SB PS ST. Contributed reagents/materials/analysis tools: PS. Wrote the manuscript: SB PS ST. Recruitment: SB PS DZ TK MM TG.