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Research Article

Comparison of Blood RNA Extraction Methods Used for Gene Expression Profiling in Amyotrophic Lateral Sclerosis

  • Nadhim Bayatti,

    Affiliation: Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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  • Johnathan Cooper-Knock,

    Affiliation: Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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  • Joanna J. Bury,

    Affiliation: Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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  • Matthew Wyles,

    Affiliation: Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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  • Paul R. Heath,

    Affiliation: Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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  • Janine Kirby,

    Affiliation: Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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  • Pamela J. Shaw mail

    pamela.shaw@sheffield.ac.uk

    Affiliation: Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

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  • Published: January 27, 2014
  • DOI: 10.1371/journal.pone.0087508

About the Authors

Nadhim Bayatti, Johnathan Cooper-Knock, Joanna J. Bury, Matthew Wyles, Paul R. Heath, Janine Kirby, Pamela J. Shaw
Sheffield Institute for Translational Neuroscience, Department of Neuroscience, University of Sheffield, Sheffield, United Kingdom

Corresponding Author

Email: pamela.shaw@sheffield.ac.uk

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NB JJB JC-K PRH JK PJS. Performed the experiments: NB JC-K JJB MW PRH. Analyzed the data: NB JC-K JJB MW PRH JK PJS. Wrote the paper: NB PRH JK PJS.