About the Authors

Phing-How Lou

Affiliation Postdoctoral Fellow, Cardiovascular Research Centre, University of Alberta, Edmonton, AB, Canada

Eliana Lucchinetti

Affiliation Research Associate, Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB, Canada

Liyan Zhang

Affiliation Research Associate, Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB, Canada

Andreas Affolter

Affiliation Research Associate, Department of Clinical Chemistry, University Children’s Hospital Zurich, Zurich, Switzerland

Marcus C. Schaub

Affiliation Professor, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland

Manoj Gandhi

Affiliation Research Associate, Department of Pharmacology, University of Alberta, Edmonton, AB, Canada

Martin Hersberger

Affiliation Head of the Department of Clinical Chemistry, University Children’s Hospital Zurich, Zurich, Switzerland

Blair E. Warren

Affiliation Undergraduate student, Campus Saint-Jean, University of Alberta, Edmonton, AB, Canada

Hélène Lemieux

Affiliation Assistant Professor, Campus Saint-Jean, University of Alberta, Edmonton, AB, Canada

Hany F. Sobhi

Affiliation Assistant Professor and Director of Coppin Center for Organic Synthesis, Coppin State University, Baltimore, Maryland, United States of America

Alexander S. Clanachan

Contributed equally to this work with: Alexander S. Clanachan, Michael Zaugg

Affiliation Professor, Department of Pharmacology, University of Alberta, Edmonton, AB, Canada

Michael Zaugg

Contributed equally to this work with: Alexander S. Clanachan, Michael Zaugg

michael.zaugg@ualberta.ca

Affiliation Professor, Department of Anesthesiology & Pain Medicine, University of Alberta, Edmonton, AB, Canada

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EL AC MZ HL. Performed the experiments: PHL LZ AA MG BEW. Analyzed the data: PHL EL MG HL. Contributed reagents/materials/analysis tools: HFS MH AC MZ. Wrote the paper: AC MZ EL MS.