About the Authors

Evelyne Israël Assayag

Affiliations Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada, Asmacure Ltée, Québec, QC, Canada

Marie-Josée Beaulieu

Affiliation Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada

Yvon Cormier

yvon.cormier@med.ulaval.ca

Affiliations Institut Universitaire de Cardiologie et de Pneumologie de Québec, Québec, QC, Canada, Asmacure Ltée, Québec, QC, Canada

Competing Interests

The authors have read the journal's policy and have the following conflicts: funding from a commercial source (Asmacure Ltée). This study was funded by Asmacure Ltée, EIA and YC are shareholders and part-time employees of Asmacure Ltée; this does not alter their adherence to all the PLOS ONE policies on sharing data and materials. Patent related to material pertinent to this article: EIA and YC are inventors and may benefit from the following patents belonging to Université Laval, Quebec City, QC. Canada: Nicotinic receptor agonists for the treatment of inflammatory diseases # US8377936 B2; US 20110301152 A1; US8551983 B2; US 8557804 B2. This does not alter their adherence to all the PLOS ONE policies on sharing data and materials. Patents, all related to the cited US patents, were granted in other countries (Australia, Canada, China, Europe, Israel, Japan, Mexico, New Zealand, Russia and South Korea). There are no further patents, products in development or marketed products to declare.

Author Contributions

Conceived and designed the experiments: EIA MJB YC. Performed the experiments: MJB. Analyzed the data: EIA MJB YC. Contributed reagents/materials/analysis tools: MJB YC. Wrote the paper: EIA YC MJB.