Up-Regulation of Tumor Necrosis Factor Superfamily Genes in Early Phases of Photoreceptor Degeneration

Sem Genini; William A. Beltran; Gustavo D. Aguirre

doi:10.1371/journal.pone.0085408

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Open Access

Peer-reviewed

Research Article

Up-Regulation of Tumor Necrosis Factor Superfamily Genes in Early Phases of Photoreceptor Degeneration

Sem Genini ,

* E-mail: geninis@vet.upenn.edu (SG); gda@vet.upenn.edu (GDA)

Affiliation Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
William A. Beltran,

Affiliation Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯
Gustavo D. Aguirre

* E-mail: geninis@vet.upenn.edu (SG); gda@vet.upenn.edu (GDA)

Affiliation Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America
⨯

Up-Regulation of Tumor Necrosis Factor Superfamily Genes in Early Phases of Photoreceptor Degeneration

Sem Genini,
William A. Beltran,
Gustavo D. Aguirre

Published: December 19, 2013
https://doi.org/10.1371/journal.pone.0085408

About the Authors

Sem Genini

* E-mail: geninis@vet.upenn.edu (SG); gda@vet.upenn.edu (GDA)

Affiliation Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

William A. Beltran

Affiliation Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Gustavo D. Aguirre

* E-mail: geninis@vet.upenn.edu (SG); gda@vet.upenn.edu (GDA)

Affiliation Section of Ophthalmology, Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SG WAB GDA. Performed the experiments: SG WAB GDA. Analyzed the data: SG WAB GDA. Contributed reagents/materials/analysis tools: SG WAB GDA. Wrote the manuscript: SG WAB GDA.

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Apoptosis
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Retina
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Gene expression
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Photoreceptors
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Cell death
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Retinal degeneration
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Dogs
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Immunohistochemistry techniques
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