Advertisement
Research Article

Deficiency of CCAAT/Enhancer Binding Protein-Epsilon Reduces Atherosclerotic Lesions in LDLR−/− Mice

  • Ryoko Okamoto,

    Affiliation: Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America

    X
  • Sigal Gery mail,

    gerys@cshs.org

    Affiliation: Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America

    X
  • Adrian F. Gombart,

    Affiliations: Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America, Department of Biochemisty and Biophysics, Linus Pauling Institute, Oregon State University, Corvallis, Oregon, United States of America

    X
  • Xuping Wang,

    Affiliation: Department of Human Genetics, Department of Medicine, and Department of Microbiology, Molecular Genetics, and Immunology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

    X
  • Lawrence W. Castellani,

    Affiliation: Department of Medicine/Division of Cardiology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

    X
  • Tadayuki Akagi,

    Affiliation: Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America

    X
  • Shuang Chen,

    Affiliation: Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

    X
  • Moshe Arditi,

    Affiliation: Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

    X
  • Quoc Ho,

    Affiliation: Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America

    X
  • Aldons J. Lusis,

    Affiliation: Department of Human Genetics, Department of Medicine, and Department of Microbiology, Molecular Genetics, and Immunology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America

    X
  • Quanlin Li,

    Affiliation: Biostatistics and Bioinformatics Research Center, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America

    X
  • H. Phillip Koeffler

    Affiliations: Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America, Cancer Science Institute of Singapore and National Cancer Institute, National University of Singapore, Singapore, Singapore

    X
  • Published: January 28, 2014
  • DOI: 10.1371/journal.pone.0085341

About the Authors

Ryoko Okamoto, Sigal Gery, Adrian F. Gombart, Tadayuki Akagi, Quoc Ho, H. Phillip Koeffler
Division of Hematology and Oncology, Cedars-Sinai Medical Center, University of California Los Angeles (UCLA) School of Medicine, Los Angeles, California, United States of America
Adrian F. Gombart
Department of Biochemisty and Biophysics, Linus Pauling Institute, Oregon State University, Corvallis, Oregon, United States of America
Xuping Wang, Aldons J. Lusis
Department of Human Genetics, Department of Medicine, and Department of Microbiology, Molecular Genetics, and Immunology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America
Lawrence W. Castellani
Department of Medicine/Division of Cardiology, David Geffen School of Medicine at University of California Los Angeles (UCLA), Los Angeles, California, United States of America
Shuang Chen, Moshe Arditi
Division of Pediatric Infectious Diseases and Immunology, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
Quanlin Li
Biostatistics and Bioinformatics Research Center, Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America
H. Phillip Koeffler
Cancer Science Institute of Singapore and National Cancer Institute, National University of Singapore, Singapore, Singapore

Corresponding Author

Email: gerys@cshs.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: RO AFG HPK. Performed the experiments: RO XW TA SC QH. Analyzed the data: RO SG HPK. Contributed reagents/materials/analysis tools: LWC MA AJL QL. Wrote the manuscript: RO SG HPK.