About the Authors

Anne Cori

Affiliation MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom

Helen Ayles

Affiliations ZAMBART, University of Zambia, School of Medicine, Ridgeway Campus, Lusaka, Zambia, Department of Clinical Research, London School of Hygiene and Tropical Medicine, London, United Kingdom

Nulda Beyers

Affiliation Desmond Tutu TB Centre, Department of Paediatrics and Child Health, Stellenbosch University, Stellenbosch, South Africa

Ab Schaap

Affiliations ZAMBART, University of Zambia, School of Medicine, Ridgeway Campus, Lusaka, Zambia, Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

Sian Floyd

Affiliation Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

Kalpana Sabapathy

Affiliation Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

Jeffrey W. Eaton

Affiliation MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom

Katharina Hauck

Affiliation Business School, Imperial College London, South Kensington, London, United Kingdom

Peter Smith

Affiliation Business School, Imperial College London, South Kensington, London, United Kingdom

Sam Griffith

Affiliation FHI 360, Research Triangle Park, North Carolina, United States of America

Ayana Moore

Affiliation FHI 360, Research Triangle Park, North Carolina, United States of America

Deborah Donnell

Affiliation Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Sten H. Vermund

Affiliation Vanderbilt Institute for Global Health and Department of Pediatrics, Vanderbilt University, Nashville, Tennessee, United States of America

Sarah Fidler

Affiliation Department of Medicine, Imperial College London, London, United Kingdom

Richard Hayes

Affiliation Department of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, United Kingdom

Christophe Fraser

c.fraser@imperial.ac.uk

Affiliation MRC Centre for Outbreak Analysis and Modelling, Department of Infectious Disease Epidemiology, Imperial College London, London, United Kingdom

HPTN 071 (PopART) study team

Membership of the HPTN 071 (PopART) study team is provided in the Acknowledgments.

Competing Interests

The authors declare that co-author Sten Vermund is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: AC, HA, NB, AS, S. Floyd, KS, KH, PS, SG, AM, DD, SHV, S. Fidler, RH, CF. Performed the experiments: AC. Analyzed the data: AC CF. Contributed reagents/materials/analysis tools: AC JWE CF. Wrote the paper: AC JWE CF. Contributed to revising the manuscript and approved the final version: AC, HA, NB, AS, S. Floyd, KS, JWE, KH, PS, SG, AM, DD, SHV, S. Fidler, RH, CF.