About the Authors
- Stephanie M. Marshall
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Affiliations Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America, Department of Cellular and Molecular Medicine, Cleveland Clinic Foundation – Lerner Research Institute, Cleveland, Ohio, United States of America
- Kathryn L. Kelley
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Affiliation Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
- Matthew A. Davis
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Affiliation Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
- Martha D. Wilson
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Affiliation Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
- Allison L. McDaniel
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Affiliation Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
- Richard G. Lee
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Affiliation Cardiovascular Group, Antisense Drug Discovery, Isis Pharmaceuticals, Carlsbad, California, United States of America
- Rosanne M. Crooke
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Affiliation Cardiovascular Group, Antisense Drug Discovery, Isis Pharmaceuticals, Carlsbad, California, United States of America
- Mark J. Graham
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Affiliation Cardiovascular Group, Antisense Drug Discovery, Isis Pharmaceuticals, Carlsbad, California, United States of America
- Lawrence L. Rudel
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Affiliation Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America
- J. Mark Brown
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Contributed equally to this work with: J. Mark Brown, Ryan E. Temel
* E-mail: brownm5@ccf.org (JMB); ryan.temel@uky.edu (RT)
Affiliations Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America, Department of Cellular and Molecular Medicine, Cleveland Clinic Foundation – Lerner Research Institute, Cleveland, Ohio, United States of America
- Ryan E. Temel
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Contributed equally to this work with: J. Mark Brown, Ryan E. Temel
* E-mail: brownm5@ccf.org (JMB); ryan.temel@uky.edu (RT)
Affiliations Department of Pathology, Section on Lipid Sciences, Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States of America, Saha Cardiovascular Research Center, University of Kentucky, Lexington, Kentucky, United States of America
Competing Interests
The authors have read the journal's policy and have the following conflicts. R.M.C., R.G.L., and M.J.D. are employees of and have ownership interest in Isis Pharmaceuticals. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: SMM JMB RET. Performed the experiments: SMM KLK MAD MDW ALM. Analyzed the data: SMM JMB RET. Contributed reagents/materials/analysis tools: RGL RMC MJG LLR. Wrote the paper: SMM JMB RET.