About the Authors

Jie Ding

jid12@dsmz.de

Affiliation Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany

Julia Romani

Affiliation Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany

Margarete Zaborski

Affiliation Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany

Roderick A. F. MacLeod

Affiliation Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany

Stefan Nagel

Affiliation Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany

Hans G. Drexler

Affiliation Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany

Hilmar Quentmeier

Affiliation Leibniz-Institute DSMZ-German Collection of Microorganisms and Cell Cultures, Department of Human and Animal Cell Lines, Braunschweig, Germany

Competing Interests

The authors have the following interest. Novartis Pharmaceuticals (Basel, Switzerland) provided the nilotinib and BEZ235 for this study. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: JD HQ. Performed the experiments: JD JR MZ SN RM. Analyzed the data: JD HQ RM. Contributed reagents/materials/analysis tools: SN HD. Wrote the manuscript: JD HQ.