Widespread Misinterpretable ChIP-seq Bias in Yeast

Daechan Park; Yaelim Lee; Gurvani Bhupindersingh; Vishwanath R. Iyer

doi:10.1371/journal.pone.0083506

Loading metrics

Open Access

Peer-reviewed

Research Article

Widespread Misinterpretable ChIP-seq Bias in Yeast

Daechan Park,

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America
⨯
Yaelim Lee,

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America
⨯
Gurvani Bhupindersingh,

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America
⨯
Vishwanath R. Iyer

* E-mail: vishy.iyer@gmail.com)

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America
⨯

Widespread Misinterpretable ChIP-seq Bias in Yeast

Daechan Park,
Yaelim Lee,
Gurvani Bhupindersingh,
Vishwanath R. Iyer

Published: December 9, 2013
https://doi.org/10.1371/journal.pone.0083506

About the Authors

Daechan Park

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America

Yaelim Lee

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America

Gurvani Bhupindersingh

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America

Vishwanath R. Iyer

* E-mail: vishy.iyer@gmail.com)

Affiliation Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, Department of Molecular Biosciences, University of Texas, Austin, Texas, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DP YL VRI. Performed the experiments: DP YL GB. Analyzed the data: DP YL. Wrote the manuscript: DP YL VRI.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

DNA transcription
Is the Subject Area "DNA transcription" applicable to this article?

Thanks for your feedback.
Chromatin
Is the Subject Area "Chromatin" applicable to this article?

Thanks for your feedback.
Yeast
Is the Subject Area "Yeast" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
Immunoprecipitation
Is the Subject Area "Immunoprecipitation" applicable to this article?

Thanks for your feedback.
RNA sequencing
Is the Subject Area "RNA sequencing" applicable to this article?

Thanks for your feedback.
Gene prediction
Is the Subject Area "Gene prediction" applicable to this article?

Thanks for your feedback.