About the Authors

Mira Katan

mira.katan@usz.ch

Affiliations Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, United States of America, Department of Neurology, University Hospital of Zurich, Switzerland

Yeseon P. Moon

Affiliation Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, United States of America

Myunghee C. Paik

Affiliation Department of Biostatistics, Mailman School of Public Health, Columbia University New York, New York, United States of America

Robert L. Wolfert

Affiliation diaDexus, Inc., San Francisco, California, United States of America

Ralph L. Sacco

Affiliations Department of Neurology, Miller School of Medicine, University of Miami, Miami, Florida, United States of America, Departments of Epidemiology and Human Genetics, Miller School of Medicine, University of Miami, Miami, Florida, United States of America

Mitchell S. V. Elkind

Affiliations Department of Neurology, Columbia University College of Physicians and Surgeons, New York, New York, United States of America, Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York, United States of America

Competing Interests

The authors have read the journals policy and have the following disclosures: Dr. Katan has received an unconditional research grant form BRAHMS part of Thermo Fisher Scientific up to 2011. Ms Yeseon P. Moon has no disclosures. Dr. Myunghee C. Paik has no disclosures. Dr. Wolfert is a former employee of diaDexus, manufacturer of the PLAC Test for Lp-PLA2. Dr. Ralph Sacco received research support from NINDS for the Northern Manhattan Study (R37 NS 29993) and support from the Evelyn McKnight Brain Institute. Dr. Elkind receives compensation for serving on an event adjudication committee for Jarvik Heart; receives research support from diaDexus, Inc., Bristol-Myers Squibb/Sanofi Pharmaceuticals Partnership, and the NIH/NINDS; has given expert legal opinions on behalf of Organon (NuvaRing® and stroke litigation) and GlaxoSmithKline (Avandia® and stroke litigation); and serves as Resident and Fellow Section Editor for Neurology, for which he receives compensation from the AAN. This does not alter their adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: MK YPM MCP RLS MSVE. Performed the experiments: MK YPM MCP RLS MSVE. Analyzed the data: MK YPM MCP RLS MSVE. Contributed reagents/materials/analysis tools: RLW RLS MSVE. Wrote the paper: MK YPM MSVE. Revised the manuscript critically for important intellectual content and approved this submitted version: MK YPM MCP RLW RLS MSVE. Funding for this study was provided by: MK MSVE.