About the Authors
- Alessandra Di Penta
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Contributed equally to this work with: Alessandra Di Penta, Asako Chiba
Affiliations Neurogenomiks Laboratory, University of Basque Country (UPV/ EHU), Zamudio, Spain, Achucarro Basque Center for Neuroscience, Zamudio, Spain
- Asako Chiba
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Contributed equally to this work with: Alessandra Di Penta, Asako Chiba
Affiliations Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan
- Iraide Alloza
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Affiliations Neurogenomiks Laboratory, University of Basque Country (UPV/ EHU), Zamudio, Spain, Achucarro Basque Center for Neuroscience, Zamudio, Spain, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain
- Ane Wyssenbach
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Affiliation Neurotek Laboratory, University of Basque Country (UPV/EHU), Zamudio, Spain
- Takashi Yamamura
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Affiliation Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan
- Pablo Villoslada
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Affiliation Center of Neuroimmunology, Institute of Biomedical Research August Pi Sunyer (IDIBAPS) – Hospital Clinic of Barcelona, Barcelona, Spain
- Sachiko Miyake
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Affiliations Department of Immunology, National Institute of Neuroscience, National Center of Neurology and Psychiatry, Tokyo, Japan, Department of Immunology, Juntendo University School of Medicine, Tokyo, Japan
- Koen Vandenbroeck
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* E-mail: k.vandenbroeck@ikerbasque.org
Affiliations Neurogenomiks Laboratory, University of Basque Country (UPV/ EHU), Zamudio, Spain, Achucarro Basque Center for Neuroscience, Zamudio, Spain, IKERBASQUE, Basque Foundation for Science, Bilbao, Spain
Competing Interests
The authors declare that Pablo Villoslada, as one of the co-authors of the manuscript, is a PLOS ONE Editorial Board. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Performed the experiments: AdP AC AW. Analyzed the data: AdP AC IA TY PV SM KV. Contributed reagents/materials/analysis tools: KV PV SM TY. Wrote the manuscript: AdP AC SM KV. Carried out the microscopy, molecular studies, organotypic cultures, EAE model and performed the statistical analysis: AdP AC. Performed astrocytes cultures: AW. Participated in the design and interpretation of the study: AdP AC IA PV SM TY KV. Read and approved the final manuscript: AdP AC IA AW PV SM TY KV.