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Research Article

Functional Complementation of sir2Δ Yeast Mutation by the Human Orthologous Gene SIRT1

  • Davide Gaglio,

    Affiliations: Department of Biology and Biotechnology Charles Darwin, Sapienza-Università di Roma, Rome, Italy, Istituto Pasteur - Fondazione Cenci Bolognetti, Sapienza-Università di Roma, Rome, Italy

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  • Anna D’Alfonso,

    Affiliation: Department of Biology and Biotechnology Charles Darwin, Sapienza-Università di Roma, Rome, Italy

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  • Giorgio Camilloni mail

    giorgio.camilloni@uniroma1.it

    Affiliations: Department of Biology and Biotechnology Charles Darwin, Sapienza-Università di Roma, Rome, Italy, Istituto Pasteur - Fondazione Cenci Bolognetti, Sapienza-Università di Roma, Rome, Italy, Institute of Molecular Biology and Pathology, The National Research Council (CNR), Rome, Italy

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  • Published: December 11, 2013
  • DOI: 10.1371/journal.pone.0083114

About the Authors

Davide Gaglio, Anna D’Alfonso, Giorgio Camilloni
Department of Biology and Biotechnology Charles Darwin, Sapienza-Università di Roma, Rome, Italy
Davide Gaglio, Giorgio Camilloni
Istituto Pasteur - Fondazione Cenci Bolognetti, Sapienza-Università di Roma, Rome, Italy
Giorgio Camilloni
Institute of Molecular Biology and Pathology, The National Research Council (CNR), Rome, Italy

Corresponding Author

Email: giorgio.camilloni@uniroma1.it

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DG AD GC. Performed the experiments: DG AD. Analyzed the data: DG AD GC. Contributed reagents/materials/analysis tools: DG GC. Wrote the manuscript: DG AD GC.