About the Authors
- Hui Zhi
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Affiliation Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Ivan Luptak
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Affiliation Boston University School of Medicine, Boston, Massachusetts, United States of America
- Gaurav Alreja
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Affiliation Boston University School of Medicine, Boston, Massachusetts, United States of America
- Jianru Shi
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Current address: Division of Cardiovascular Medicine, Keck School of medicine, University of Southern California, Los Angeles, California, United States of America
Affiliation Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Jian Guan
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Affiliation Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
- Nicole Metes-Kosik
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Affiliation VA Boston Healthcare System, West Roxbury, Massachusetts, United States of America
- Jacob Joseph
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* E-mail: jjoseph16@partners.org
Affiliations VA Boston Healthcare System, West Roxbury, Massachusetts, United States of America, Boston University School of Medicine, Boston, Massachusetts, United States of America, Brigham and Womens Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Competing Interests
The work was supported by a resarch grant from Novartis Pharmaceuticals. Dr. Joseph has received research grants from Novartis Pharmaceuticals, which manufactures the drug aliskiren, used in this study. There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Conceived and designed the experiments: JJ HZ IL NM-K. Performed the experiments: HZ NM-K GA JS JG IL. Analyzed the data: JJ NM-K IL GA HZ. Contributed reagents/materials/analysis tools: JS JG. Wrote the paper: HZ JJ.