About the Authors

Sandra A. Acosta

Contributed equally to this work with: Sandra A. Acosta, Steven Wolfe, Naoki Tajiri

Affiliation Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America

David M. Diamond

Affiliations James A. Haley Veterans Affairs Medical Center, Tampa, Florida, United States of America, Department of Psychology, Center for Preclinical & Clinical Research on PTSD, Department of Molecular Pharmacology and Physiology, University of South Florida, Tampa, Florida, United States of America

Steven Wolfe

Contributed equally to this work with: Sandra A. Acosta, Steven Wolfe, Naoki Tajiri

Affiliation James A. Haley Veterans Affairs Medical Center, Tampa, Florida, United States of America

Naoki Tajiri

Contributed equally to this work with: Sandra A. Acosta, Steven Wolfe, Naoki Tajiri

Affiliation Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America

Kazutaka Shinozuka

Affiliation Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America

Hiroto Ishikawa

Affiliation Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America

Diana G. Hernandez

Affiliation Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America

Paul R. Sanberg

Affiliations Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America, Office of Research and Innovation, University of South Florida, Tampa, Florida, United States of America

Yuji Kaneko

Affiliation Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America

Cesar V. Borlongan

cborlong@health.usf.edu

Affiliation Center of Excellence for Aging and Brain Repair, Department of Neurosurgery and Brain Repair, University of South Florida College of Medicine, Tampa, Florida, United States of America

Competing Interests

This work was supported by a grant from the Department of Defense and intramural support from the USF Veterans Reintegration Committee and the Neuroscience Collaborative program. The opinions expressed in this publication are those of the authors and not of the Department of Veterans Affairs or the US government. Senior author Dr. Cesar Borlongan is a PLOS ONE Editorial Board member. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: CVB DMD PRS. Performed the experiments: SAA SW NT KS HI DGH CVB. Analyzed the data: SAA NT CVB. Contributed reagents/materials/analysis tools: DMD PRS YK CVB. Wrote the paper: SAA DMD CVB. Designed psychosocial stress paradigm: DD. Contributed analysis: PRS YK.