About the Authors

Il Kwon

Contributed equally to this work with: Il Kwon, Sung-Yu Hong

Affiliations Department of Neurology, Yonsei University College of Medicine, Seoul, Korea, Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea

Sung-Yu Hong

Contributed equally to this work with: Il Kwon, Sung-Yu Hong

Affiliations Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea, Cardiovascular Product Evaluation Center, Yonsei University College of Medicine, Seoul, Korea

Young Dae Kim

Affiliations Department of Neurology, Yonsei University College of Medicine, Seoul, Korea, Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea

Hyo Suk Nam

Affiliations Department of Neurology, Yonsei University College of Medicine, Seoul, Korea, Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea

Sungsoo Kang

Affiliations Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea, Cardiovascular Product Evaluation Center, Yonsei University College of Medicine, Seoul, Korea

Seung-Hee Yang

Affiliations Department of Neurology, Yonsei University College of Medicine, Seoul, Korea, Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea

Ji Hoe Heo

jhheo@yuhs.ac

Affiliations Department of Neurology, Yonsei University College of Medicine, Seoul, Korea, Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University College of Medicine, Seoul, Korea, Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea

Competing Interests

The authors have read the journal's policy and have the following conflicts. Yonsei University to which the authors (Il Kwon, Sung-Yu Hong, Young Dae Kim, and Ji Hoe Heo) are affiliated has patent applications pending for saxatilin (Composition for Thrombolysis and Pharmaceutical Composition for Treating Diseases related to Blood Vessel Occlusion or Narrowness Comprising the Same; Korean Patent Application No. 10-2010-0107760, PCT/KR2011/008248, U.S. Patent Application No. 13/882,792, European Patent Application No. 11838212.6, Chinese Application for Invention No. 201180052931.0, and Japanese Patent Registration No. 51300921196). This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: IK SYH JHH. Performed the experiments: IK SYH SSK SHY. Analyzed the data: IK SYH YDK HSN SSK JHH. Contributed reagents/materials/analysis tools: IK SYH JHH. Wrote the manuscript: IK SYH JHH.