About the Authors

Hongwei Shao

Affiliations Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America, Department of Modern Mechanics, University of Science and Technology of China, Hefei, Anhui, P.R. China

Tao Peng

Affiliation Department of Translational Imaging, The Methodist Hospital Research Institute, Houston, Texas, United States of America

Zhiwei Ji

Affiliation Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America

Jing Su

Affiliation Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America

Xiaobo Zhou

xizhou@wakehealth.edu

Affiliation Department of Radiology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XZ HS TP. Analyzed the data: HS TP JS. Wrote the paper: HS TP. Performed the mathematical modeling and optimization: HS TP ZJ. Reviewed the scientific content and approved the final version of the manuscript: XZ HS ZJ.