About the Authors

Holly M. Nguyen

Contributed equally to this work with: Holly M. Nguyen, Nazanin Ruppender

Affiliation Department of Urology, University of Washington, Seattle, Washington, United States of America

Nazanin Ruppender

Contributed equally to this work with: Holly M. Nguyen, Nazanin Ruppender

Affiliation Department of Urology, University of Washington, Seattle, Washington, United States of America

Xiaotun Zhang

Affiliation Department of Urology, University of Washington, Seattle, Washington, United States of America

Lisha G. Brown

Affiliation Department of Urology, University of Washington, Seattle, Washington, United States of America

Ted S. Gross

Affiliation Department of Orthopedics, University of Washington, Seattle, Washngton, United States of America

Colm Morrissey

Affiliation Department of Urology, University of Washington, Seattle, Washington, United States of America

Roman Gulati

Affiliation Biostatistics and Biomathematics Program, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Robert L. Vessella

Affiliation Department of Urology, University of Washington, Seattle, Washington, United States of America

Frauke Schimmoller

Affiliation Exelixis Inc, South San Francisco, California, United States of America

Dana T. Aftab

Affiliation Exelixis Inc, South San Francisco, California, United States of America

Eva Corey

ecorey@uw.edu

Affiliation Department of Urology, University of Washington, Seattle, Washington, United States of America

Competing Interests

This study was partly funded by Exelixis Inc., the employer of Frauke Schimmoller and Dana T. Aftab. Eva Corey has received research funding from Exelixis, Inc., via Sponsored Research Agreement with the University of Washington. There are no patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.

Author Contributions

Conceived and designed the experiments: EC RLV FS DTA. Performed the experiments: HMN LGB XZ TSG. Analyzed the data: EC LGB CM RG TSG DTA FS NR. Contributed reagents/materials/analysis tools: DTA FS RG EC RLV CM TSG. Wrote the manuscript: NR EC RLV CM RG DTA FS.