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Research Article

Multipotent Nestin-Positive Stem Cells Reside in the Stroma of Human Eccrine and Apocrine Sweat Glands and Can Be Propagated Robustly In Vitro

  • Sabine Nagel,

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Franziska Rohr,

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Caroline Weber,

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Janina Kier,

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Frank Siemers,

    Affiliation: Department of Plastic and Hand Surgery, University of Lübeck, Lübeck, Germany

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  • Charli Kruse,

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Sandra Danner,

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Matthias Brandenburger equal contributor mail,

    equal contributor Contributed equally to this work with: Matthias Brandenburger, Anna Emilia Matthiessen

    Matthias.Brandenburger@emb.fraunhofer.de

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Anna Emilia Matthiessen equal contributor

    equal contributor Contributed equally to this work with: Matthias Brandenburger, Anna Emilia Matthiessen

    Affiliation: Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany

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  • Published: October 24, 2013
  • DOI: 10.1371/journal.pone.0078365

About the Authors

Sabine Nagel, Franziska Rohr, Caroline Weber, Janina Kier, Charli Kruse, Sandra Danner, Matthias Brandenburger, Anna Emilia Matthiessen
Fraunhofer Research Institution for Marine Biotechnology, Lübeck, Germany
Frank Siemers
Department of Plastic and Hand Surgery, University of Lübeck, Lübeck, Germany

Corresponding Author

Email: Matthias.Brandenburger@emb.fraunhofer.de

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SN CK SD AEM. Performed the experiments: SN FR CW. Analyzed the data: SN FR CW SD AEM. Contributed reagents/materials/analysis tools: JK FS. Wrote the manuscript: SN SD MB AEM.