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Research Article

Experimental Induction of Pulmonary Fibrosis in Horses with the Gammaherpesvirus Equine Herpesvirus 5

  • Kurt J. Williams mail,

    williamsk@dcpah.msu.edu

    Affiliation: Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

    X
  • N. Edward Robinson,

    Affiliation: Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

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  • Ailam Lim,

    Affiliation: Diagnostic Center for Population and Animal Health, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Christina Brandenberger,

    Affiliation: Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Roger Maes,

    Affiliation: Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Ashley Behan,

    Affiliation: Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Steven R. Bolin

    Affiliation: Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

    X
  • Published: October 11, 2013
  • DOI: 10.1371/journal.pone.0077754

About the Authors

Kurt J. Williams, Christina Brandenberger, Roger Maes, Steven R. Bolin
Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America
N. Edward Robinson, Ashley Behan
Large Animal Clinical Sciences, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America
Ailam Lim
Diagnostic Center for Population and Animal Health, College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, United States of America

Corresponding Author

Email: williamsk@dcpah.msu.edu

Competing Interests

This study was funded by Pfizer Animal Health, New York, N.Y. There are no other declarations to be made related to employment, consultancy, patents, products in development etc. related to this manuscript. The authors' relationship with Pfizer Animal Health does not alter their adherence to all PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: KJW SRB NER AB RM AL. Performed the experiments: KJW SRB. Analyzed the data: KJW SRB RM AL CB. Contributed reagents/materials/analysis tools: KJW SRB CB. Wrote the manuscript: KJW SRB. Clinical management of animals: NER AB.