Can Antidepressants Prevent Pegylated Interferon-α/Ribavirin-Associated Depression in Patients with Chronic Hepatitis C: Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Trials?

Xin-Jiang Hou; Jing-Hang Xu; Jun Wang; Yan-Yan Yu

doi:10.1371/journal.pone.0076799

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Open Access

Peer-reviewed

Research Article

Can Antidepressants Prevent Pegylated Interferon-α/Ribavirin-Associated Depression in Patients with Chronic Hepatitis C: Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Trials?

Xin-Jiang Hou,

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China
⨯
Jing-Hang Xu,

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China
⨯
Jun Wang,

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China
⨯
Yan-Yan Yu

* E-mail: yyy@bjmu.edu.cn

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China
⨯

Can Antidepressants Prevent Pegylated Interferon-α/Ribavirin-Associated Depression in Patients with Chronic Hepatitis C: Meta-Analysis of Randomized, Double-Blind, Placebo-Controlled Trials?

Xin-Jiang Hou,
Jing-Hang Xu,
Jun Wang,
Yan-Yan Yu

Published: October 30, 2013
https://doi.org/10.1371/journal.pone.0076799

About the Authors

Xin-Jiang Hou

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China

Jing-Hang Xu

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China

Jun Wang

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China

Yan-Yan Yu

* E-mail: yyy@bjmu.edu.cn

Affiliation Department of Infectious Diseases, Peking University First Hospital, Peking University, Beijing, People's Republic of China

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: XJH YYY. Performed the experiments: XJH JHX. Analyzed the data: XJH JW. Contributed reagents/materials/analysis tools: JHX JW. Wrote the paper: XJH YYY.

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Depression
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Antiviral therapy
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Antidepressants
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Antidepressant drug therapy
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Prophylaxis
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Metaanalysis
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Adverse events
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Epidemiology
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