About the Authors

David A. G. Skibinski

Contributed equally to this work with: David A. G. Skibinski, Brendon J. Hanson

Current address: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore

Affiliations A*STAR Program in Translational Research on Infectious Disease, Agency for Science, Technology and Research, Singapore, Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Brendon J. Hanson

Contributed equally to this work with: David A. G. Skibinski, Brendon J. Hanson

Affiliation Defence Science Organisation (DSO) National Laboratories, Singapore

Yufang Lin

Affiliation Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Veronika von Messling

Affiliation Institut National de la Recherche Scientifique (INRS)- Institut Armand-Frappier, University of Quebec, Quebec, Canada

Andrea Jegerlehner

Affiliation Cytos Biotechnology AG, Zurich, Switzerland

Jason Boon Sern Tee

Affiliation Defence Science Organisation (DSO) National Laboratories, Singapore

De Hoe Chye

Affiliation Defence Science Organisation (DSO) National Laboratories, Singapore

Steven K. K. Wong

Affiliation Defence Science Organisation (DSO) National Laboratories, Singapore

Amanda A. P. Ng

Affiliations A*STAR Program in Translational Research on Infectious Disease, Agency for Science, Technology and Research, Singapore, Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Hui Yin Lee

Affiliation Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Bijin Au

Affiliation Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Bernett T. K. Lee

Affiliation Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Lucia Santoso

Affiliation Experimental Therapeutics Centre (ETC), Agency for Science, Technology and Research, Singapore

Michael Poidinger

Affiliation Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Anna-Marie Fairhurst

Affiliation Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Alex Matter

Affiliation Experimental Therapeutics Centre (ETC), Agency for Science, Technology and Research, Singapore

Martin F. Bachmann

Current address: University Hospital ZŸrich, ZŸrich, Switzerland

Affiliation Cytos Biotechnology AG, Zurich, Switzerland

Philippe Saudan

Affiliation Cytos Biotechnology AG, Zurich, Switzerland

John E. Connolly

jeconnolly@imcb.a-star.edu.sg

Current address: Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology and Research (A*STAR), Singapore

Affiliations A*STAR Program in Translational Research on Infectious Disease, Agency for Science, Technology and Research, Singapore, Singapore Immunology Network (SIgN), Agency for Science, Technology and Research, Singapore

Competing Interests

The authors declare that Philippe Saudan is currently employed by Cytos Biotechnology AG and holds stocks or stock options in Cytos Biotechnology AG. Andrea Jegerlehner and Martin Bachmann are former employees of Cytos Biotechnology AG but are no longer affiliated with this company. Andrea Jegerlehner holds stocks or stock options in Cytos Biotechnology AG. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: DAGS BJH YL VvM AJ AM MFB PS JEC. Performed the experiments: DAGS BJH YL VvM AJ JBST DHC SKKW AAPN HYL BA A-MF. Analyzed the data: DAGS BJH VvM BA BTKL LS MP. Contributed reagents/materials/analysis tools: AJ MFB PS. Wrote the paper: DAGS JEC.