About the Authors

Evan L. Brittain

evan.brittain@vanderbilt.edu

Affiliation Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Meredith E. Pugh

Affiliation Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Li Wang

Affiliation Department of Biostatistics, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Alex L. Newman

Affiliation Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Ivan M. Robbins

Affiliation Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

John H. Newman

Affiliation Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Anna R. Hemnes

Affiliation Division of Pulmonary and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Competing Interests

MEP has performed consulting: Gilead; ARH has funding from Pfizer, United Therapeutics, and consulting: Actelion, United Therapeutics and Pfizer. ELB, LW, AN, IMR, and JHN all report no competing interests. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EB MP LW AN IR JN AH. Performed the experiments: EB MP AN AH. Analyzed the data: EB MP LW AH. Contributed reagents/materials/analysis tools: EB MP LW AH. Wrote the manuscript: EB MP LW AN JN AH.