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Research Article

MicroRNA-150 Expression Induces Myeloid Differentiation of Human Acute Leukemia Cells and Normal Hematopoietic Progenitors

  • Valerie A. Morris,

    Affiliations: Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Hematology, Department of Medicine, University of Washington, Seattle, Washington, United States of America

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  • Ailin Zhang,

    Affiliation: Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Taimei Yang,

    Affiliation: Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Derek L. Stirewalt,

    Affiliation: Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Ranjani Ramamurthy,

    Affiliation: Department of Medicine, University of Washington, Seattle, Washington, United States of America

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  • Soheil Meshinchi,

    Affiliation: Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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  • Vivian G. Oehler mail

    voehler@u.washington.edu

    Affiliations: Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Division of Hematology, Department of Medicine, University of Washington, Seattle, Washington, United States of America

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  • Published: September 24, 2013
  • DOI: 10.1371/journal.pone.0075815

About the Authors

Valerie A. Morris, Ailin Zhang, Taimei Yang, Derek L. Stirewalt, Soheil Meshinchi, Vivian G. Oehler
Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
Valerie A. Morris, Vivian G. Oehler
Division of Hematology, Department of Medicine, University of Washington, Seattle, Washington, United States of America
Ranjani Ramamurthy
Department of Medicine, University of Washington, Seattle, Washington, United States of America

Corresponding Author

Email: voehler@u.washington.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: VGO VAM. Performed the experiments: VAM TY AZ RR. Analyzed the data: VGO VAM RR. Contributed reagents/materials/analysis tools: DS SM RR. Wrote the manuscript: VGO VAM.