About the Authors
- Yosuke Nakatani
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Affiliations Tsukuba Research Laboratories, Eisai Co, Ltd., Tsukuba, Ibaraki, Japan, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Chiba, Japan, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan
- Michiyuki Suzuki
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Affiliations Tsukuba Research Laboratories, Eisai Co, Ltd., Tsukuba, Ibaraki, Japan, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Chiba, Japan
- Masaki Tokunaga
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Affiliation Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Chiba, Japan
- Jun Maeda
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Affiliation Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Chiba, Japan
- Miyuki Sakai
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Affiliation Tsukuba Research Laboratories, Eisai Co, Ltd., Tsukuba, Ibaraki, Japan
- Hiroki Ishihara
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Affiliation Tsukuba Research Laboratories, Eisai Co, Ltd., Tsukuba, Ibaraki, Japan
- Takashi Yoshinaga
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Affiliation Tsukuba Research Laboratories, Eisai Co, Ltd., Tsukuba, Ibaraki, Japan
- Osamu Takenaka
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Affiliation Tsukuba Research Laboratories, Eisai Co, Ltd., Tsukuba, Ibaraki, Japan
- Ming-Rong Zhang
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Affiliations Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Chiba, Japan, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan
- Tetsuya Suhara
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Affiliations Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Chiba, Japan, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan
- Makoto Higuchi
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* E-mail: mhiguchi@nirs.go.jp
Affiliations Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Chiba, Japan, Graduate School of Medicine, Tohoku University, Sendai, Miyagi, Japan
Competing Interests
YN, M. Suzuki, M. Sakai, HI, TY and OT are affiliated with Eisai Co., Ltd. E2110 is a compound in development by Eisai Co., Ltd. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials. No additional competing interests exist.
Author Contributions
Conceived and designed the experiments: YN TS MH. Performed the experiments: YN M. Suzuki MT JM M. Sakai HI TY OT MRZ MH. Analyzed the data: YN M. Suzuki MT M. Sakai HI TY OT. Contributed reagents/materials/analysis tools: MRZ. Wrote the manuscript: YN MH.