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Research Article

The Non-Structural NS1 Protein Unique to Respiratory Syncytial Virus: A Two-State Folding Monomer in Quasi-Equilibrium with a Stable Spherical Oligomer

  • Esteban Pretel,

    Affiliation: Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina

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  • Gabriela Camporeale,

    Affiliation: Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina

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  • Gonzalo de Prat-Gay mail

    gpg@leloir.org.ar

    Affiliation: Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina

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  • Published: September 10, 2013
  • DOI: 10.1371/journal.pone.0074338

About the Authors

Esteban Pretel, Gabriela Camporeale, Gonzalo de Prat-Gay
Protein Structure-Function and Engineering Laboratory, Fundación Instituto Leloir and IIBBA-CONICET, Buenos Aires, Argentina

Corresponding Author

Email: gpg@leloir.org.ar

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: EP GC GDPG. Performed the experiments: EP GC. Analyzed the data: EP GC GDPG. Wrote the paper: EP GDPG.