About the Authors

Francois-Pierre J. Martin

francois-pierre.martin@rd.nestle.com (FPJM); serge.rezzi@rd.nestle.com (SR)

Current address: Molecular Biomarkers, Nestlé Institute of Health Sciences SA, Lausanne, Switzerland

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Ivan Montoliu

Affiliation Applied Mathematics, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Sebastiano Collino

Current address: Molecular Biomarkers, Nestlé Institute of Health Sciences SA, Lausanne, Switzerland

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Max Scherer

Current address: Molecular Biomarkers, Nestlé Institute of Health Sciences SA, Lausanne, Switzerland

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Philippe Guy

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Isabelle Tavazzi

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Anita Thorimbert

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Sofia Moco

Current address: Natural Bioactives and Screening, Nestlé Institute of Health Sciences SA, Lausanne, Switzerland

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Megan P. Rothney

Affiliation Diagnostics and Biomedical Technology Organization, GE Global Research Center, Niskayuna, New York, United States of America

David L. Ergun

Affiliation GE Healthcare, Madison, Wisconsin, United States of America

Maurice Beaumont

Affiliation Clinical Development Unit, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Fiona Ginty

Affiliation GE Healthcare, Madison, Wisconsin, United States of America

Salah D. Qanadli

Affiliation Cardiothoracic and Vascular Unit, Department of Radiology, University Hospital of Lausanne, Lausanne, Switzerland

Lucie Favre

Affiliation Service of Endocrinology, Diabetology and Metabolism, Department of Medicine, University Hospital of Lausanne, Lausanne, Switzerland

Vittorio Giusti

Affiliation Service of Endocrinology, Diabetology and Metabolism, Department of Medicine, University Hospital of Lausanne, Lausanne, Switzerland

Serge Rezzi

francois-pierre.martin@rd.nestle.com (FPJM); serge.rezzi@rd.nestle.com (SR)

Current address: Natural Bioactives and Screening, Nestlé Institute of Health Sciences SA, Lausanne, Switzerland

Affiliation Metabolomics and Biomarkers, Nestec Ltd., Nestle Research Center, Lausanne, Switzerland

Competing Interests

Authors FPM, SC, MS, SM, PG, IT, AT, SR are employees of Nestlé Institute of Health Science SA. Authors IM, MB are employees of Nestec S.A. Authors MPR, DLE, FG are employees of GE. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FPJM SR VG. Performed the experiments: FPJM SC PG IT AT MB SDQ LF VG. Analyzed the data: FPJM IM MS SM MPR DLE FG MB SDQ. Contributed reagents/materials/analysis tools: FPJM SC MS PG IT AT SM MB MPR DLE. Wrote the paper: FPJM IM SC MS SM MB VG SR.