About the Authors

John A. Ronald

Affiliations Molecular Imaging Program at Stanford, Stanford University, Stanford, California, United States of America, Department of Radiology, Stanford University, Stanford, California, United States of America

Lorena Cusso

Affiliation Departamento de Bioingeniería e Ingeniería Aeroespacial, Universidad Carlos III de Madrid, Instituto de Investigación Sanitaria Gregorio Marañón, CIBERSAM, Madrid, Spain

Hui-Yen Chuang

Affiliations Molecular Imaging Program at Stanford, Stanford University, Stanford, California, United States of America, National Yang-Ming University, Taipei, Taiwan

Xinrui Yan

Affiliations Molecular Imaging Program at Stanford, Stanford University, Stanford, California, United States of America, Department of Radiology, Stanford University, Stanford, California, United States of America

Anca Dragulescu-Andrasi

Affiliations Molecular Imaging Program at Stanford, Stanford University, Stanford, California, United States of America, Department of Radiology, Stanford University, Stanford, California, United States of America

Sanjiv Sam Gambhir

sgambhir@stanford.edu

Affiliations Molecular Imaging Program at Stanford, Stanford University, Stanford, California, United States of America, Department of Radiology, Stanford University, Stanford, California, United States of America

Competing Interests

The authors declare the following provisional patent related to the submitted manuscript: Application Number: 61734005; Title: Development of Non-Integrative Replicating Minicircles for Safe Reporter Gene Imaging of Cell-Based Therapies. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: JAR XY AD SSG. Performed the experiments: JAR LC HC XY AD. Analyzed the data: JAR LC HC. Contributed reagents/materials/analysis tools: JAR. Wrote the paper: JAR LC AD SSG.