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Research Article

The Human Urine Metabolome

  • Souhaila Bouatra,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Farid Aziat,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Rupasri Mandal,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • An Chi Guo,

    Affiliation: Department of Computing Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Michael R. Wilson,

    Affiliation: Department of Computing Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Craig Knox,

    Affiliation: Department of Computing Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Trent C. Bjorndahl,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Ramanarayan Krishnamurthy,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Fozia Saleem,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Philip Liu,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Zerihun T. Dame,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Jenna Poelzer,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Jessica Huynh,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Faizath S. Yallou,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Nick Psychogios,

    Affiliation: Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

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  • Edison Dong,

    Affiliation: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada

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  • Ralf Bogumil,

    Affiliation: BIOCRATES Life Sciences AG, Innsbruck, Austria

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  • Cornelia Roehring,

    Affiliation: BIOCRATES Life Sciences AG, Innsbruck, Austria

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  • David S. Wishart mail

    david.wishart@ualberta.ca

    Affiliations: Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada, Department of Computing Sciences, University of Alberta, Edmonton, Alberta, Canada, National Institute for Nanotechnology, Edmonton, Alberta, Canada

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  • Published: September 04, 2013
  • DOI: 10.1371/journal.pone.0073076

About the Authors

Souhaila Bouatra, Farid Aziat, Rupasri Mandal, Trent C. Bjorndahl, Ramanarayan Krishnamurthy, Fozia Saleem, Philip Liu, Zerihun T. Dame, Jenna Poelzer, Jessica Huynh, Faizath S. Yallou, Edison Dong, David S. Wishart
Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada
An Chi Guo, Michael R. Wilson, Craig Knox, David S. Wishart
Department of Computing Sciences, University of Alberta, Edmonton, Alberta, Canada
Nick Psychogios
Cardiovascular Research Center, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, United States of America
Ralf Bogumil, Cornelia Roehring
BIOCRATES Life Sciences AG, Innsbruck, Austria
David S. Wishart
National Institute for Nanotechnology, Edmonton, Alberta, Canada

Corresponding Author

Email: david.wishart@ualberta.ca

Competing Interests

Ralf Bogumil and Cornelia Roehring are employed by BIOCRATES Life Sciences AG. This company produces kits for targeted metabolomic analyses. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: SB FA RM RK DSW. Performed the experiments: SB FA RM RK ZTD NP RB CR. Analyzed the data: SB FA RM RK ACG ZTD DSW. Contributed reagents/materials/analysis tools: ACG MRW CK TCB FS PL ZTD JP JH FSY ED RB CR DSW. Wrote the paper: SB FA RM RK TCB FS PL NP DSW.