Hepatocellular Proliferation Correlates with Inflammatory Cell and Cytokine Changes in a Murine Model of Nonalchoholic Fatty Liver Disease

Michael N. VanSaun; Alisha M. Mendonsa; D. Lee Gorden

doi:10.1371/journal.pone.0073054

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Peer-reviewed

Research Article

Hepatocellular Proliferation Correlates with Inflammatory Cell and Cytokine Changes in a Murine Model of Nonalchoholic Fatty Liver Disease

Michael N. VanSaun ,

Contributed equally to this work with: Michael N. VanSaun, Alisha M. Mendonsa

Affiliations Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
Alisha M. Mendonsa ,

Contributed equally to this work with: Michael N. VanSaun, Alisha M. Mendonsa

Affiliation Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯
D. Lee Gorden

* E-mail: lee.gorden@vanderbilt.edu

Affiliations Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America
⨯

Hepatocellular Proliferation Correlates with Inflammatory Cell and Cytokine Changes in a Murine Model of Nonalchoholic Fatty Liver Disease

Michael N. VanSaun,
Alisha M. Mendonsa,
D. Lee Gorden

Published: September 9, 2013
https://doi.org/10.1371/journal.pone.0073054

About the Authors

Michael N. VanSaun

Contributed equally to this work with: Michael N. VanSaun, Alisha M. Mendonsa

Affiliations Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America, Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

Alisha M. Mendonsa

Contributed equally to this work with: Michael N. VanSaun, Alisha M. Mendonsa

Affiliation Department of Cancer Biology, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America

D. Lee Gorden

* E-mail: lee.gorden@vanderbilt.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: MNV AMM DLG. Performed the experiments: MNV AMM. Analyzed the data: MNV AMM DLG. Contributed reagents/materials/analysis tools: MNV AMM DLG. Wrote the paper: MNV AMM DLG.

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Fatty liver
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Cytokines
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Inflammation
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Hepatocytes
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Steatosis
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Mouse models
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Diet
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Hepatocellular carcinoma
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