About the Authors

Eleftheria Mavridou

MavridouRita@gmail.com (EM); p.verweij@mmb.umcn.nl (PEV)

Affiliations Department of Medical Microbiology, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands

Joseph Meletiadis

Affiliation Laboratory for Clinical Microbiology, Attikon University General Hospital, Athens, Greece

Pavol Jancura

Affiliation Institute for Computing and Information Sciences, Faculty of Science, Radboud University, Nijmegen, The Netherlands

Saiden Abbas

Affiliation Institute for Computing and Information Sciences, Faculty of Science, Radboud University, Nijmegen, The Netherlands

Maiken C. Arendrup

Affiliation Department of Microbiological Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark

Willem J. G. Melchers

Affiliations Department of Medical Microbiology, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands

Tom Heskes

Affiliation Institute for Computing and Information Sciences, Faculty of Science, Radboud University, Nijmegen, The Netherlands

Johan W. Mouton

Affiliations Department of Medical Microbiology, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands

Paul E. Verweij

MavridouRita@gmail.com (EM); p.verweij@mmb.umcn.nl (PEV)

Affiliations Department of Medical Microbiology, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands, Nijmegen Institute for Infection, Inflammation and Immunity, Nijmegen, The Netherlands

Competing Interests

This study was funded by Merck Sharp & Dohme (MSD). There are no patents, products in development or marketed products to declare. This does not alter the authors′ adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: EM JM JWM PEV. Performed the experiments: EM. Analyzed the data: EM JM JWM PJ SA TH. Contributed reagents/materials/analysis tools: WJGM MCA. Wrote the paper: EM JM PJ JWM PEV. Provided molecular data: WJGM. Designed and supervised the mathematical analysis: TH. Critical revision for important intellectual content: MCA.