Advertisement
Research Article

Uroplakin Peptide-Specific Autoimmunity Initiates Interstitial Cystitis/Painful Bladder Syndrome in Mice

  • Kenan Izgi,

    Affiliations: Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Clinical Chemistry, Cleveland State University, Cleveland,, Ohio, United States of America

    X
  • Cengiz Z. Altuntas,

    Affiliation: Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America

    Current address: Texas Institute of Biotechnology Education and Research, North American College, Houston, Texas, United States of America

    X
  • Fuat Bicer,

    Affiliations: Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Clinical Chemistry, Cleveland State University, Cleveland,, Ohio, United States of America

    X
  • Ahmet Ozer,

    Affiliations: Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America, Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Cagri Sakalar,

    Affiliation: Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

    X
  • Xiaoxia Li,

    Affiliation: Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

    X
  • Vincent K. Tuohy,

    Affiliation: Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

    X
  • Firouz Daneshgari mail

    fxd22@case.edu

    Affiliation: Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America

    X
  • Published: August 16, 2013
  • DOI: 10.1371/journal.pone.0072067

About the Authors

Kenan Izgi, Cengiz Z. Altuntas, Fuat Bicer, Ahmet Ozer, Firouz Daneshgari
Department of Urology, Case Western Reserve University, Cleveland, Ohio, United States of America
Kenan Izgi, Fuat Bicer
Department of Clinical Chemistry, Cleveland State University, Cleveland,, Ohio, United States of America
Ahmet Ozer
Department of Genetics, Case Western Reserve University, Cleveland, Ohio, United States of America
Cagri Sakalar, Xiaoxia Li, Vincent K. Tuohy
Department of Immunology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, United States of America

Corresponding Author

Email: fxd22@case.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: CZA XL VKT FD. Performed the experiments: KI CZA FB AO. Analyzed the data: KI CZA CS XL VKT FD. Wrote the paper: KI CZA CS VKT FD.