About the Authors

Patrício Soares Costa

Contributed equally to this work with: Patrício Soares Costa, Nadine Correia Santos

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

Nadine Correia Santos

Contributed equally to this work with: Patrício Soares Costa, Nadine Correia Santos

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

Pedro Cunha

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal, Centro Hospital Alto Ave – EPE, Guimarães, Portugal

Joana Almeida Palha

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

Nuno Sousa

njcsousa@ecsaude.uminho.pt

Affiliations Life and Health Sciences Research Institute (ICVS), School of Health Sciences, University of Minho, Braga, Portugal, ICVS/3B’s, PT Government Associate Laboratory, Braga/Guimarães, Portugal

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: NS JAP. Performed the experiments: NCS PC. Analyzed the data: PSC NCS. Contributed reagents/materials/analysis tools: PSC. Wrote the paper: PSC NCS NS. Participated in data interpretation and contributed substantially to the scientific process leading up to the writing of the submitted manuscript and have approved of its final version: PSC NCS PC JAP NS.