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Research Article

Proteomic Analysis of Signaling Network Regulation in Renal Cell Carcinomas with Differential Hypoxia-Inducible Factor-2α Expression

  • Lokesh Dalasanur Nagaprashantha,

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    Current address: Department of Diabetes and Metabolic Disease Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

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  • Tatjana Talamantes,

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

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  • Jyotsana Singhal,

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    Current address: Department of Diabetes and Metabolic Disease Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

    X
  • Jia Guo,

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    Current address: Biological Sciences Division, Pacific Northwest National Laboratory, Richland, Washington, United States of America

    X
  • Rit Vatsyayan,

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    Current address: Department of Cellular and Molecular Biology, The University of Texas Health Science Center at Tyler, Texas, United States of America

    X
  • Navin Rauniyar,

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    Current address: Department of Chemical Physiology, The Scripps Research Institute, La Jolla, California, United States of America

    X
  • Sanjay Awasthi,

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    Current address: Department of Diabetes and Metabolic Disease Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

    X
  • Sharad S. Singhal equal contributor,

    equal contributor Contributed equally to this work with: Sharad S. Singhal, Laszlo Prokai

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    Current address: Department of Diabetes and Metabolic Disease Research, Beckman Research Institute, City of Hope National Medical Center, Duarte, California, United States of America

    X
  • Laszlo Prokai equal contributor mail

    equal contributor Contributed equally to this work with: Sharad S. Singhal, Laszlo Prokai

    Laszlo.Prokai@unthsc.edu

    Affiliation: Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

    X
  • Published: August 05, 2013
  • DOI: 10.1371/journal.pone.0071654

About the Authors

Lokesh Dalasanur Nagaprashantha, Tatjana Talamantes, Jyotsana Singhal, Jia Guo, Rit Vatsyayan, Navin Rauniyar, Sanjay Awasthi, Sharad S. Singhal, Laszlo Prokai
Department of Molecular Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas, United States of America

Corresponding Author

Email: Laszlo.Prokai@unthsc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LDN SSS LP. Performed the experiments: LDN JS RV. Analyzed the data: LDN TT JG NR. Contributed reagents/materials/analysis tools: SA SSS LP. Wrote the paper: LDN TT SSS LP.