About the Authors

Daniel H. Madsen

daniel.madsen@nih.gov

Affiliations The Finsen Laboratory, Rigshospitalet/Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark, Proteases and Tissue Remodeling Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

Henrik J. Jürgensen

Affiliation The Finsen Laboratory, Rigshospitalet/Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Signe Ingvarsen

Current address: Antibody Technology, Biopharmaceutical Research Unit, Novo Nordisk A/S, Måløv, Denmark

Affiliation The Finsen Laboratory, Rigshospitalet/Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Maria C. Melander

Affiliation The Finsen Laboratory, Rigshospitalet/Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Reidar Albrechtsen

Affiliation Department of Biomedical Sciences & Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Andreas Hald

Affiliation The Finsen Laboratory, Rigshospitalet/Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Kenn Holmbeck

Affiliation Matrix Metalloproteinase Unit, Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

Thomas H. Bugge

Affiliation Proteases and Tissue Remodeling Section, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland, United States of America

Niels Behrendt

Affiliation The Finsen Laboratory, Rigshospitalet/Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Lars H. Engelholm

Affiliation The Finsen Laboratory, Rigshospitalet/Biotech Research and Innovation Centre, University of Copenhagen, Copenhagen, Denmark

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: DHM RA THB NB LHE. Performed the experiments: DHM HJJ SI MCM AH KH. Analyzed the data: DHM RA KH NB LHE. Wrote the paper: DHM NB LHE.