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Research Article

Efficiency of Household Reactive Case Detection for Malaria in Rural Southern Zambia: Simulations Based on Cross-Sectional Surveys from Two Epidemiological Settings

  • Kelly M. Searle,

    Affiliation: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Timothy Shields,

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Harry Hamapumbu,

    Affiliation: Macha Research Trust, Choma, Zambia

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  • Tamaki Kobayashi,

    Affiliation: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Sungano Mharakurwa,

    Affiliations: W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America, Macha Research Trust, Choma, Zambia

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  • Philip E. Thuma,

    Affiliation: Macha Research Trust, Choma, Zambia

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  • David L. Smith,

    Affiliation: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Gregory Glass,

    Affiliation: W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • William J. Moss mail

    wmoss@jhsph.edu

    Affiliations: Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America, W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America

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  • Published: August 06, 2013
  • DOI: 10.1371/journal.pone.0070972

About the Authors

Kelly M. Searle, Tamaki Kobayashi, David L. Smith, William J. Moss
Department of Epidemiology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
Timothy Shields, Sungano Mharakurwa, Gregory Glass, William J. Moss
W. Harry Feinstone Department of Molecular Microbiology and Immunology, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
Harry Hamapumbu, Sungano Mharakurwa, Philip E. Thuma
Macha Research Trust, Choma, Zambia

Corresponding Author

Email: wmoss@jhsph.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KMS TS GG WJM. Performed the experiments: KMS TS HH TK SM PET DLS GG WJM. Analyzed the data: KMS TS DLS GG WJM. Wrote the paper: KMS TS DLS GG WJM.