About the Authors
- Sungeun Kim
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Affiliations Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Shanker Swaminathan
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Affiliations Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Mark Inlow
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Affiliations Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Mathematics, Rose-Hulman Institute of Technology, Terre Haute, Indiana, United States of America
- Shannon L. Risacher
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Affiliation Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Kwangsik Nho
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Affiliation Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Li Shen
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Affiliations Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Tatiana M. Foroud
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Affiliations Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Ronald C. Petersen
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Affiliation Department of Neurology, Mayo Clinic, Rochester, Minnesota, United States of America
- Paul S. Aisen
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Affiliation Department of Neurology, University of California San Diego, San Diego, California, United States of America
- Holly Soares
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Affiliation Bristol Myers Squibb Co, Wallingford, Connecticut, United States of America
- Jon B. Toledo
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Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
- Leslie M. Shaw
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Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
- John Q. Trojanowski
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Affiliation Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America
- Michael W. Weiner
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Affiliations Departments of Radiology, Medicine and Psychiatry, University of California, San Francisco, San Francisco, California, United States of America, Department of Veterans Affairs Medical Center, San Francisco, California, United States of America
- Brenna C. McDonald
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Affiliation Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Martin R. Farlow
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Affiliation Department of Neurology, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Bernardino Ghetti
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Affiliation Department of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- Andrew J. Saykin
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* E-mail: asaykin@iupui.edu
Affiliations Center for Neuroimaging, Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Center for Computational Biology and Bioinformatics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America, Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States of America
- for the Alzheimer’s Disease Neuroimaging Initiative (ADNI)
Competing Interests
ADNI is funded in part through generous contributions from the following: Abbott; Alzheimer’s Association; Alzheimer’s Drug Discovery Foundation; Amorfix Life Sciences Ltd.; AstraZeneca; Bayer HealthCare; BioClinica, Inc.; Biogen Idec Inc.; Bristol-Myers Squibb Company; Eisai Inc.; Elan Pharmaceuticals Inc.; Eli Lilly and Company; F. Hoffmann-La Roche Ltd and its affiliated company Genentech, Inc.; GE Healthcare; Innogenetics, N.V.; IXICO Ltd.; Janssen Alzheimer Immunotherapy Research & Development, LLC.; Johnson & Johnson Pharmaceutical Research Development LLC.; Medpace, Inc.; Merck & Co., Inc.; Meso Scale Diagnostics, LLC.; Novartis Pharmaceuticals Corporation; Pfizer Inc.; Servier; Synarc Inc.; and Takeda Pharmaceutical Company. However, no funding from any commercial source, listed in the paper, was directly received by the authors. Co-author Holly Soares is employed by Bristol Myers Squibb Co. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: SK AJS MI. Performed the experiments: SK MI SS SLR KN LS. Analyzed the data: SK SS MI AJS. Contributed reagents/materials/analysis tools: SLR KN TF RCP PSA HS JBT LMS JQT MWW BCM MRF BG. Wrote the paper: SK SS MI SLR JQT AJS.