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Research Article

Ron Knockdown and Ron Monoclonal Antibody IMC-RON8 Sensitize Pancreatic Cancer to Histone Deacetylase Inhibitors (HDACi)

  • Yi Zou,

    Affiliation: Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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  • Gillian M. Howell,

    Affiliation: Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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  • Lisa E. Humphrey,

    Affiliation: Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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  • Jing Wang,

    Affiliation: Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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  • Michael G. Brattain mail

    mbrattain@unmc.edu

    Affiliation: Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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  • Published: July 29, 2013
  • DOI: 10.1371/journal.pone.0069992

About the Authors

Yi Zou, Gillian M. Howell, Lisa E. Humphrey, Jing Wang, Michael G. Brattain
Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

Corresponding Author

Email: mbrattain@unmc.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YZ MGB. Performed the experiments: YZ LEH. Analyzed the data: YZ GMH MGB. Contributed reagents/materials/analysis tools: YZ GMH JW MGB. Wrote the paper: YZ MGB.