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Research Article

National Surveillance Study on Carbapenem Non-Susceptible Klebsiella pneumoniae in Taiwan: The Emergence and Rapid Dissemination of KPC-2 Carbapenemase

  • Sheng-Kang Chiu,

    Affiliations: Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC, Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, ROC

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  • Tsu-Lan Wu,

    Affiliation: Department of Laboratory Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan, ROC

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  • Yin-Ching Chuang,

    Affiliation: Department of Medical Research, Chi Mei Medical Center, Tainan Hsien, Taiwan, ROC

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  • Jung-Chung Lin,

    Affiliation: Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

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  • Chang-Phone Fung,

    Affiliation: Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, National Yan-Ming University, Taipei, Taiwan, ROC

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  • Po-Liang Lu,

    Affiliation: Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC

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  • Jann-Tay Wang,

    Affiliation: Division of Infectious Diseases, Department of Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC

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  • Lih-Shinn Wang,

    Affiliation: Department of Infectious Diseases, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, ROC

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  • L. Kristopher Siu,

    Affiliation: Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan, ROC

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  • Kuo-Ming Yeh mail

    kmyeh@ndmctsgh.edu.tw

    Affiliation: Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC

    X
  • Published: July 24, 2013
  • DOI: 10.1371/journal.pone.0069428

About the Authors

Sheng-Kang Chiu, Jung-Chung Lin, Kuo-Ming Yeh
Division of Infectious Diseases and Tropical Medicine, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, ROC
Sheng-Kang Chiu
Graduate Institute of Medical Sciences, National Defense Medical Center, Taipei, Taiwan, ROC
Tsu-Lan Wu
Department of Laboratory Medicine, Chang Gung Memorial Hospital, Kweishan, Taoyuan, Taiwan, ROC
Yin-Ching Chuang
Department of Medical Research, Chi Mei Medical Center, Tainan Hsien, Taiwan, ROC
Chang-Phone Fung
Section of Infectious Diseases, Department of Medicine, Taipei Veterans General Hospital, National Yan-Ming University, Taipei, Taiwan, ROC
Po-Liang Lu
Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan, ROC
Jann-Tay Wang
Division of Infectious Diseases, Department of Medicine, National Taiwan University Hospital, Taipei, Taiwan, ROC
Lih-Shinn Wang
Department of Infectious Diseases, Buddhist Tzu Chi General Hospital, Hualien, Taiwan, ROC
L. Kristopher Siu
Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli, Taiwan, ROC

Corresponding Author

Email: kmyeh@ndmctsgh.edu.tw

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SKC TLW YCC JCL CPF PLL JTW LSW LKS KMY. Performed the experiments: SKC TLW PLL JTW LKS. Analyzed the data: SKC YCC CPF PLL LKS KMY. Wrote the paper: SKC JCL LKS KMY.