About the Authors
- Alessio Atzori
-
Affiliation School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
- Audrey E. Baker
-
Affiliation Biologics Research, Janssen Research and Development Inc., Radnor, Pennsylvania, United States of America
- Mark Chiu
-
Affiliation Biologics Research, Janssen Research and Development Inc., Radnor, Pennsylvania, United States of America
- Richard A. Bryce
-
* E-mail: r.a.bryce@manchester.ac.uk (RB); pascal.bonnet@univ-orleans.fr (PB)
Affiliation School of Pharmacy and Pharmaceutical Sciences, University of Manchester, Manchester, United Kingdom
- Pascal Bonnet
-
* E-mail: r.a.bryce@manchester.ac.uk (RB); pascal.bonnet@univ-orleans.fr (PB)
Current address: Université d’Orléans, Centre National de la Recherche Scientifique, Institut de Chimie Organique et Analytique, Orléans, France
Affiliation Janssen Research & Development, a division of Janssen Pharmaceutica N.V., Beerse, Belgium
Competing Interests
Authors AEB, MC and PB are employed by Janssen Research and Development, a division of Janssen Pharmaceutica N.V. There are no patents, products in development or marketed products to declare. This does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials, as detailed online in the guide for authors.
Author Contributions
Wrote the paper: RB PB AA AEB. Conceived and designed the study: PB RB. Performed model building and molecular dynamics simulations: AA. Analyzed simulations: AA RB PB. Performed circular dichroism experiments and analysis: MC AEB.