About the Authors

Kevin Drew

Contributed equally to this work with: Kevin Drew, P. Douglas Renfrew

Affiliation Department of Biology, Center for Genomics and Systems Biology, New York University, New York, New York, United States of America

P. Douglas Renfrew

Contributed equally to this work with: Kevin Drew, P. Douglas Renfrew

Affiliation Department of Biology, Center for Genomics and Systems Biology, New York University, New York, New York, United States of America

Timothy W. Craven

Affiliation Department of Biology, Center for Genomics and Systems Biology, New York University, New York, New York, United States of America

Glenn L. Butterfoss

Affiliation Department of Biology, Center for Genomics and Systems Biology, New York University, New York, New York, United States of America

Fang-Chieh Chou

Affiliation Department of Biochemistry, Stanford University, Stanford, California, United States of America

Sergey Lyskov

Affiliation Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America

Brooke N. Bullock

Affiliation Department of Chemistry, New York University, New York, New York, United States of America

Andrew Watkins

Affiliation Department of Chemistry, New York University, New York, New York, United States of America

Jason W. Labonte

Affiliation Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America

Michael Pacella

Affiliation Department of Biomedical Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America

Krishna Praneeth Kilambi

Affiliation Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America

Andrew Leaver-Fay

Affiliation Department of Biochemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America

Brian Kuhlman

Affiliation Department of Biochemistry, University of North Carolina, Chapel Hill, North Carolina, United States of America

Jeffrey J. Gray

Affiliations Department of Chemical and Biomolecular Engineering, The Johns Hopkins University, Baltimore, Maryland, United States of America, Program in Molecular Biophysics, The Johns Hopkins University, Baltimore, Maryland, United States of America

Philip Bradley

Affiliation Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

Kent Kirshenbaum

Affiliation Department of Chemistry, New York University, New York, New York, United States of America

Paramjit S. Arora

Affiliation Department of Chemistry, New York University, New York, New York, United States of America

Rhiju Das

Affiliation Department of Biochemistry, Stanford University, Stanford, California, United States of America

Richard Bonneau

bonneau@nyu.edu

Affiliations Department of Biology, Center for Genomics and Systems Biology, New York University, New York, New York, United States of America, Computer Science Department, Courant Institute of Mathematical Sciences, New York University, New York, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: KD PDR FCC JWL JJG KK PSA RD RB. Performed the experiments: KD PDR TWC FCC JWL BNB AW MP KPK. Analyzed the data: KD PDR TWC GLB FCC JWL MP KPK. Contributed reagents/materials/analysis tools: ALF BK PB KK PSA. Wrote the paper: KD PDR FCC JWL KK PSA RD RB. Contributed software for server: SL.