About the Authors
- Bo Xu
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Affiliation Research Program Infection and Cancer, DKFZ, Heidelberg, Germany
- Sasithorn Chotewutmontri
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Current address: Genomics and Proteomics Core Facility, DKFZ, Heidelberg, Germany
Affiliation Research Program Infection and Cancer, DKFZ, Heidelberg, Germany
- Stephan Wolf
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Affiliation Genomics and Proteomics Core Facility, DKFZ, Heidelberg, Germany
- Ursula Klos
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Affiliation Research Program Infection and Cancer, DKFZ, Heidelberg, Germany
- Martina Schmitz
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Current address: Oncgnostics GmbH, Jena, Germany
Affiliation Department for Gynecology, Jena University Hospital, Jena, Germany
- Matthias Dürst
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Affiliation Department for Gynecology, Jena University Hospital, Jena, Germany
- Elisabeth Schwarz
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* E-mail: e.schwarz@dkfz.de
Affiliation Research Program Infection and Cancer, DKFZ, Heidelberg, Germany
Competing Interests
Martina Schmitz, employed by the Oncgnostics company, has added the following statement: The oncgnostics GmbH is a spin-off of the University Hospital Jena. The company develops molecular cancer diagnostics based on the detection of human DNA methylation. There are no competing interests between the oncgnostics GmbH and all data and knowledge published in this manuscript. Furthermore, the oncgnostics GmbH does not benefit from this publication and will not use this publication for patents, products or marketing. The employment at the oncgnostics GmbH does not alter the authors’ adherence to all the PLOS ONE policies on sharing data and materials.
Author Contributions
Conceived and designed the experiments: BX SC ES MS MD. Performed the experiments: BX SC UK MS SW. Analyzed the data: BX SC ES MD MS. Contributed reagents/materials/analysis tools: MD MS. Wrote the paper: ES BX SC. Conceived and designed the TEN16 strategy: BX SC ES. Conceived and designed the APOT analysis: MS MD. Designed the software used in DNA junction analysis: SC.