The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells

Leah M. Okumura; Bluma J. Lesch; David C. Page

doi:10.1371/journal.pone.0066062

Loading metrics

Open Access

Peer-reviewed

Research Article

The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells

Leah M. Okumura,

Affiliations Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America, Whitehead Institute, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
Bluma J. Lesch ,

* E-mail: leschb@wi.mit.edu (BJL); dcpage@wi.mit.edu (DCP)

Affiliations Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America, Whitehead Institute, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯
David C. Page

* E-mail: leschb@wi.mit.edu (BJL); dcpage@wi.mit.edu (DCP)

Affiliations Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America, Whitehead Institute, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America
⨯

The Ligand Binding Domain of GCNF Is Not Required for Repression of Pluripotency Genes in Mouse Fetal Ovarian Germ Cells

Leah M. Okumura,
Bluma J. Lesch,
David C. Page

Published: June 7, 2013
https://doi.org/10.1371/journal.pone.0066062

About the Authors

Leah M. Okumura

Affiliations Howard Hughes Medical Institute, Chevy Chase, Maryland, United States of America, Whitehead Institute, Cambridge, Massachusetts, United States of America, Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, United States of America

Bluma J. Lesch

* E-mail: leschb@wi.mit.edu (BJL); dcpage@wi.mit.edu (DCP)

David C. Page

* E-mail: leschb@wi.mit.edu (BJL); dcpage@wi.mit.edu (DCP)

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: LMO DCP. Performed the experiments: LMO BJL. Analyzed the data: LMO BJL. Wrote the paper: LMO BJL DCP.

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Germ cells
Is the Subject Area "Germ cells" applicable to this article?

Thanks for your feedback.
Embryos
Is the Subject Area "Embryos" applicable to this article?

Thanks for your feedback.
Ovaries
Is the Subject Area "Ovaries" applicable to this article?

Thanks for your feedback.
Pluripotency
Is the Subject Area "Pluripotency" applicable to this article?

Thanks for your feedback.
Gonads
Is the Subject Area "Gonads" applicable to this article?

Thanks for your feedback.
Gene expression
Is the Subject Area "Gene expression" applicable to this article?

Thanks for your feedback.
Immunostaining
Is the Subject Area "Immunostaining" applicable to this article?

Thanks for your feedback.
Oogenesis
Is the Subject Area "Oogenesis" applicable to this article?

Thanks for your feedback.