About the Authors

Federica Villanova

Affiliations St. John's Institute of Dermatology, King's College London, London, United Kingdom, National Institute for Health Research, Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust, (NIHR GSTT/KCL) London, United Kingdom

Paola Di Meglio

Affiliations St. John's Institute of Dermatology, King's College London, London, United Kingdom, National Institute for Health Research, Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust, (NIHR GSTT/KCL) London, United Kingdom, Molecular Immunology, National Institute for Medical Research, Mill Hill, London, United Kingdom

Margaret Inokuma

Affiliation Biological Research & Development, BD Biosciences, San Jose, California, United States of America

Nima Aghaeepour

Affiliation Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

Esperanza Perucha

Current address: Academic Department of Rheumatology, King's College London, London, United Kingdom

Affiliation The Medical Research Council (MRC) Centre for Transplantation, King's College London, London, United Kingdom

Jennifer Mollon

Affiliation Division of Genetics and Molecular Medicine, Statistical Genetics Unit, King's College London, London, United Kingdom

Laurel Nomura

Affiliation Biological Research & Development, BD Biosciences, San Jose, California, United States of America

Maria Hernandez-Fuentes

Affiliations National Institute for Health Research, Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust, (NIHR GSTT/KCL) London, United Kingdom, The Medical Research Council (MRC) Centre for Transplantation, King's College London, London, United Kingdom

Andrew Cope

Affiliation Academic Department of Rheumatology, King's College London, London United Kingdom

A. Toby Prevost

Affiliation Department of Primary Care and Public Health Sciences, King's College London, London, United Kingdom

Susanne Heck

Affiliation National Institute for Health Research, Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust, (NIHR GSTT/KCL) London, United Kingdom

Vernon Maino

Affiliation Biological Research & Development, BD Biosciences, San Jose, California, United States of America

Graham Lord

Affiliations National Institute for Health Research, Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust, (NIHR GSTT/KCL) London, United Kingdom, The Medical Research Council (MRC) Centre for Transplantation, King's College London, London, United Kingdom

Ryan R. Brinkman

Affiliations Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada, Department of Medical Genetics, University of British Columbia, Vancouver, Canada

Frank O. Nestle

frank.nestle@kcl.ac.uk

Affiliations St. John's Institute of Dermatology, King's College London, London, United Kingdom, National Institute for Health Research, Comprehensive Biomedical Research Centre, Guy's & St. Thomas' NHS Foundation Trust, (NIHR GSTT/KCL) London, United Kingdom

Competing Interests

The authors have read the journal's policy and declare the following conflicts: Margaret Inokuma, Laurel Nomura, and Vernon Maino are employees of Becton Dickinson Biosciences, affiliated to Biological Research & Development, BD Biosciences, San Jose, CA, USA. Lyoplates used in this study are a customised marketed product by BD. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Conceived and designed the experiments: FON FV PDM SH MI SM NA RRB. Performed the experiments: FV PDM SH EP MI. Analyzed the data: FON FV PDM JM ATP SH RRB NA. Contributed reagents/materials/analysis tools: FON MI LN SM MHF GL AC VM. Wrote the paper: FON FV PDM SH RRB NA.