About the Authors

Shilpa Prabhakar

Contributed equally to this work with: Shilpa Prabhakar, June Goto

Affiliation Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, and Program in Neuroscience, Medical School, Boston, Massachusetts, United States of America

June Goto

Contributed equally to this work with: Shilpa Prabhakar, June Goto

Affiliation Translational Medicine Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Xuan Zuang

Affiliation Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, and Program in Neuroscience, Medical School, Boston, Massachusetts, United States of America

Miguel Sena-Esteves

Affiliation Neurology Department, Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Roderick Bronson

Affiliation Rodent Histopathology Core Facility, Harvard Medical School, Boston, Massachusetts, United States of America

Jillian Brockmann

Affiliation Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Davide Gianni

Affiliation Neurology Department, Gene Therapy Center, University of Massachusetts Medical School, Worcester, Massachusetts, United States of America

Gregory R. Wojtkiewicz

Affiliation Center for Systems Biology and Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

John W. Chen

Affiliation Center for Systems Biology and Department of Radiology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

Anat Stemmer-Rachamimov

Affiliation Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts, United States of America

David J. Kwiatkowski

Affiliation Translational Medicine Division, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts, United States of America

Xandra O. Breakefield

breakefield@hms.harvard.edu

Affiliation Molecular Neurogenetics Unit, Department of Neurology and Center for Molecular Imaging Research, Department of Radiology, Massachusetts General Hospital, and Program in Neuroscience, Medical School, Boston, Massachusetts, United States of America

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: SP JG MSE AS-R DJK XOB. Performed the experiments: SP JG XZ DG RB JB GRW. Analyzed the data: SP JG RB JWC GRW MSE AS-R DJK XOB. Contributed reagents/materials/analysis tools: SP JG JB DG MSE AS-R DJK XOB. Wrote the paper: SP JG JWC AS-R DJK XOB.