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Research Article

Exercise Challenge in Gulf War Illness Reveals Two Subgroups with Altered Brain Structure and Function

  • Rakib U. Rayhan mail,

    rur@georgetown.edu

    Affiliation: Division of Rheumatology, Immunology and Allergy, Department of Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America

    X
  • Benson W. Stevens,

    Affiliation: Department of Neurology, Center for Functional and Molecular Imaging, Georgetown University Medical Center, Washington, District of Columbia, United States of America

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  • Megna P. Raksit,

    Affiliation: Cognitive Neurogenetics Laboratory, Department of Psychology, Georgetown University, Washington, District of Columbia, United States of America

    X
  • Joshua A. Ripple,

    Affiliation: Division of Rheumatology, Immunology and Allergy, Department of Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America

    X
  • Christian R. Timbol,

    Affiliation: Division of Rheumatology, Immunology and Allergy, Department of Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America

    X
  • Oluwatoyin Adewuyi,

    Affiliation: Division of Rheumatology, Immunology and Allergy, Department of Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America

    X
  • John W. VanMeter,

    Affiliation: Department of Neurology, Center for Functional and Molecular Imaging, Georgetown University Medical Center, Washington, District of Columbia, United States of America

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  • James N. Baraniuk

    Affiliation: Division of Rheumatology, Immunology and Allergy, Department of Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America

    X
  • Published: June 14, 2013
  • DOI: 10.1371/journal.pone.0063903
  • Featured in PLOS Collections

About the Authors

Rakib U. Rayhan, Joshua A. Ripple, Christian R. Timbol, Oluwatoyin Adewuyi, James N. Baraniuk
Division of Rheumatology, Immunology and Allergy, Department of Medicine, Georgetown University Medical Center, Washington, District of Columbia, United States of America
Benson W. Stevens, John W. VanMeter
Department of Neurology, Center for Functional and Molecular Imaging, Georgetown University Medical Center, Washington, District of Columbia, United States of America
Megna P. Raksit
Cognitive Neurogenetics Laboratory, Department of Psychology, Georgetown University, Washington, District of Columbia, United States of America

Corresponding Author

Email: rur@georgetown.edu

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: JNB JWV. Performed the experiments: RR BS MR CT OA JNB. Analyzed the data: RR BS MR OA JNB JAR. Contributed reagents/materials/analysis tools: JNB. Wrote the paper: RR JNB JAR.