Kinetic Characterization of Exonuclease-Deficient Staphylococcus aureus PolC, a C-family Replicative DNA Polymerase

Indrajit Lahiri; Purba Mukherjee; Janice D. Pata

doi:10.1371/journal.pone.0063489

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Open Access

Peer-reviewed

Research Article

Kinetic Characterization of Exonuclease-Deficient Staphylococcus aureus PolC, a C-family Replicative DNA Polymerase

Indrajit Lahiri ,

Contributed equally to this work with: Indrajit Lahiri, Purba Mukherjee

Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany School of Public Health, Albany, New York, United States of America
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Purba Mukherjee ,

Contributed equally to this work with: Indrajit Lahiri, Purba Mukherjee

Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany School of Public Health, Albany, New York, United States of America
⨯
Janice D. Pata

* E-mail: jpata@wadsworth.org

Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany School of Public Health, Albany, New York, United States of America
⨯

Kinetic Characterization of Exonuclease-Deficient Staphylococcus aureus PolC, a C-family Replicative DNA Polymerase

Indrajit Lahiri,
Purba Mukherjee,
Janice D. Pata

Published: May 16, 2013
https://doi.org/10.1371/journal.pone.0063489

About the Authors

Indrajit Lahiri

Contributed equally to this work with: Indrajit Lahiri, Purba Mukherjee

Affiliations Wadsworth Center, New York State Department of Health, Albany, New York, United States of America, Department of Biomedical Sciences, University at Albany School of Public Health, Albany, New York, United States of America

Purba Mukherjee

Contributed equally to this work with: Indrajit Lahiri, Purba Mukherjee

Janice D. Pata

* E-mail: jpata@wadsworth.org

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: IL PM JDP. Performed the experiments: IL PM. Analyzed the data: IL PM JDP. Wrote the paper: IL PM JDP.

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Polymerases
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Nucleotides
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Primer extension assay
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Chemical dissociation
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Primer extension
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DNA replication
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Polymer chemistry
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Enzyme chemistry
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