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Research Article

A Survey on Data Reproducibility in Cancer Research Provides Insights into Our Limited Ability to Translate Findings from the Laboratory to the Clinic

  • Aaron Mobley,

    Affiliation: Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Suzanne K. Linder,

    Affiliation: Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Russell Braeuer,

    Affiliation: Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Lee M. Ellis mail,

    lellis@mdanderson.org (LME); lzwellin@mdanderson.org (LZ)

    Affiliations: Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America, Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Leonard Zwelling mail

    lellis@mdanderson.org (LME); lzwellin@mdanderson.org (LZ)

    Affiliation: Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

    X
  • Published: May 15, 2013
  • DOI: 10.1371/journal.pone.0063221

About the Authors

Aaron Mobley, Russell Braeuer, Lee M. Ellis
Department of Cancer Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
Suzanne K. Linder
Department of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
Lee M. Ellis
Department of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America
Leonard Zwelling
Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America

Corresponding Authors

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: AM SKL RB LME LZ. Performed the experiments: AM SKL RB LME LZ. Analyzed the data: AM SKL RB LME LZ. Contributed reagents/materials/analysis tools: SKL. Wrote the paper: AM SKL RB LME LZ.