Decreased FOXF2 mRNA Expression Indicates Early-Onset Metastasis and Poor Prognosis for Breast Cancer Patients with Histological Grade II Tumor

Peng-Zhou Kong; Fan Yang; Lin Li; Xiao-Qing Li; Yu-Mei Feng

doi:10.1371/journal.pone.0061591

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Open Access

Peer-reviewed

Research Article

Decreased FOXF2 mRNA Expression Indicates Early-Onset Metastasis and Poor Prognosis for Breast Cancer Patients with Histological Grade II Tumor

Peng-Zhou Kong,

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Fan Yang,

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Lin Li,

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Xiao-Qing Li,

Affiliations Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯
Yu-Mei Feng

* E-mail: ymfeng@tijmu.edu.cn

Affiliations Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China
⨯

Decreased FOXF2 mRNA Expression Indicates Early-Onset Metastasis and Poor Prognosis for Breast Cancer Patients with Histological Grade II Tumor

Peng-Zhou Kong,
Fan Yang,
Lin Li,
Xiao-Qing Li,
Yu-Mei Feng

Published: April 19, 2013
https://doi.org/10.1371/journal.pone.0061591

About the Authors

Peng-Zhou Kong

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Fan Yang

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Lin Li

Affiliation Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Xiao-Qing Li

Affiliations Department of Biochemistry and Molecular Biology, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, Key Laboratory of Breast Cancer Prevention and Treatment of the Ministry of Education, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China

Yu-Mei Feng

* E-mail: ymfeng@tijmu.edu.cn

Competing Interests

The authors have declared that no competing interests exist.

Author Contributions

Conceived and designed the experiments: YMF. Performed the experiments: LL XQL. Analyzed the data: PZK FY LL XQL YMF. Contributed reagents/materials/analysis tools: PZK FY LL XQL YMF. Wrote the paper: PZK YMF.

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Breast cancer
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Metastasis
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Histology
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Prostate cancer
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Prognosis
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Cancer risk factors
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Gene expression
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Transcription factors
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