About the Authors

Saskia Woudstra

s.woudstra@vumc.nl

Affiliations Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands

Marie-José van Tol

Affiliations NeuroImaging Center & Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Behavioral Neurology, Leibniz Institute for Neurobiology, Magdeburg, Germany

Zoltán Bochdanovits

Affiliations Department of Medical Genomics, VU University Medical Center, Amsterdam, The Netherlands, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands

Nic J. van der Wee

Affiliations Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands, Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands

Frans G. Zitman

Affiliation Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands

Mark A. van Buchem

Affiliations Leiden Institute for Brain and Cognition, Leiden University, Leiden, The Netherlands, Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands

Esther M. Opmeer

Affiliation NeuroImaging Center & Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands

André Aleman

Affiliations NeuroImaging Center & Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Department of Psychology, Groningen University, Groningen, The Netherlands

Brenda W. Penninx

Affiliations Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands, Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands, NeuroImaging Center & Department of Neuroscience, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands

Dick J. Veltman

Affiliations Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands

Witte J. Hoogendijk

Affiliations Department of Psychiatry, VU University Medical Center, Amsterdam, The Netherlands, Neuroscience Campus Amsterdam, VU University, Amsterdam, The Netherlands, Department of Psychiatry, Erasmus Medical Center, Rotterdam, The Netherlands

Competing Interests

N.J.A. van der Wee received speaking fees from Eli Lilly and Wyeth and served on advisory panels of Eli Lilly, Pfizer, Wyeth, and Servier. A. Aleman received an investigator-initiated unrestricted research grant from Brystol-Myers Squibb and speakers bureau honoraria from AstraZeneca, Brystol-Myers Squibb, and GlaxoSmithKline. W.J. Hoogendijk lectured and advised for, and received unrestricted research grants from, Eli Lilly, Lundbeck, Servier, Bristol-Myers Squibb, and Organon for which payments were made to the independent research foundation of GGZ inGeest. W.J. Hoogendijk holds the following patent for gene-expression profiling in peripheral blood as a biomarker for depression (Name: Means and methods for typing a cell isolate of an individual suffering from a psychiatric disorder or at risk of suffering there from; Number: PCT/NL2008/050837; Date: December 19, 2008 [19.12.2008]).There are no further patents, products in development or marketed products to declare. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials.

Author Contributions

Interpretation of data and critical revision of the manuscript: ZB NJvdW FGZ MAvB EMO AA BWP DJV WJH. Conceived and designed the experiments: NJvdW FGZ MAvB AA BWP DJV WJH. Performed the experiments: SW MJvT DJV. Analyzed the data: SW MJvT ZB DJV. Wrote the paper: SW MJvT DJV.